June 1, 2022 Issue of JAMA Dermatology

June 2022, Vol 158, No. 6, Pages 601-708

Viewpoint

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis鈥擟oordinating Research Priorities to Move the Field Forward

Elizabeth J. Phillips, MD; Charles S. Bouchard, MD, MA; Sherrie J. Divito, MD, PhD

Abstract Full Text

JAMA Dermatol. 2022;158(6):607-608. doi:10.1001/jamadermatol.2022.0484

This Viewpoint describes the successes and gaps in research and clinical care of Steven-Johnson syndrome and toxic epidermal necrolysis.

The Power of a Palliative Perspective in Dermatology

Christopher S. Yang, BA; Victor L. Quan, MD; Alexandra Charrow, MD, MBE

Abstract Full Text

JAMA Dermatol. 2022;158(6):609-610. doi:10.1001/jamadermatol.2022.1298

This Viewpoint explores several opportunities for the integration of palliative care and dermatology.

Editorial

Rubella Virus鈥揂ssociated Granulomas in Immunocompetent Adults鈥擯ossible Implications

Luigi D. Notarangelo, MD

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JAMA Dermatol. 2022;158(6):611-613. doi:10.1001/jamadermatol.2022.0055

Original Investigation

Assessment of Frequency of Rosacea Subtypes in Patients With Rosacea: A Systematic Review and Meta-analysis

Yousef A. Barakji, MS; Amalie Thorsti Møller Rønnstad, MS; Maria O. Christensen, MD; et al.

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JAMA Dermatol. 2022;158(6):617-625. doi:10.1001/jamadermatol.2022.0526

This systematic review and meta-analysis of 39 studies assesses the frequency of the 4 major subtypes in more than 9000 patients with rosacea.

Association of Persistent Rubella Virus With Idiopathic Skin Granulomas in Clinically Immunocompetent Adults

Karolyn A. Wanat, MD; Ludmila Perelygina, PhD; Min-hsin Chen, MS; et al.

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JAMA Dermatol. 2022;158(6):626-633. doi:10.1001/jamadermatol.2022.0828

This case series study examines the association between rubella virus and atypical granulomatous inflammation in immune-competent adults.

Risk of Invasive Cutaneous Squamous Cell Carcinoma After Different Treatments for Actinic Keratosis: A Secondary Analysis of a Randomized Clinical Trial

Shima Ahmady, MD; Maud H. E. Jansen, MD, PhD; Patty J. Nelemans, MD, PhD; et al.

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JAMA Dermatol. 2022;158(6):634-640. doi:10.1001/jamadermatol.2022.1034

This secondary analysis of a randomized clinical trial evaluates the risk of invasive cutaneous squamous cell carcinoma after 4 different treatments for patients with multiple actinic keratoses.

Evaluation of Nomacopan for Treatment of Bullous Pemphigoid: A Phase 2a Nonrandomized Controlled Trial

Christian D. Sadik, MD, PhD; Hanan Rashid, MD; Christoph M. Hammers, MD, PhD; et al.

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JAMA Dermatol. 2022;158(6):641-649. doi:10.1001/jamadermatol.2022.1156

This nonrandomized controlled trial assessed the safety and therapeutic benefits of nomacopan in older adults with bullous pemphigoid.

Risks of Comorbidities in Patients With Palmoplantar Pustulosis vs Patients With Psoriasis Vulgaris or Pompholyx in Korea

Dong Hyo Kim, MD; Jin Yong Lee, MD, PhD; Soo Ick Cho, MD, PhD; et al.

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JAMA Dermatol. 2022;158(6):650-660. doi:10.1001/jamadermatol.2022.1081

This cross-sectional study uses data from the Korean National Health Insurance database and the National Health Screening Program to assess the risks of comorbidities among patients with palmoplantar pustulosis compared with patients with psoriasis vulgaris or pompholyx in Korea.

Association of Leukocyte Adhesion and Rolling in Skin With Patient Outcomes After Hematopoietic Cell Transplantation Using Noninvasive Reflectance Confocal Videomicroscopy

Inga Saknite, PhD; James R. Patrinely, MD; Zijun Zhao, MD; et al.

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JAMA Dermatol. 2022;158(6):661-669. doi:10.1001/jamadermatol.2022.0924

This cohort study identifies a quantitative characteristic of leukocyte-endothelial interactions after hematopoietic cell transplantation and tests its associations with patient outcomes.

Video: Adherent and Rolling Leukocytes in Intact Cutaneous Microvasculature via Confocal Videomicroscopy

Brief Report

Clinical and Serological Characterization of Orf-Induced Immunobullous Disease

Kaan Yilmaz, MD; Stephanie Goletz, PhD; Henri H. Pas, PhD; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(6):670-674. doi:10.1001/jamadermatol.2022.0290

This case series characterizes the predominant autoantigen in Orf-induced immunobullous disease and further describes this clinical entity.

Dermatopathologist Perceptions of Overdiagnosis of Melanocytic Skin Lesions and Association With Diagnostic Behaviors

Kathleen F. Kerr, PhD; Megan M. Eguchi, MPH; Michael W. Piepkorn, MD, PhD; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(6):675-679. doi:10.1001/jamadermatol.2022.0489

This survey study examines practicing US dermatopathologists鈥� perceptions of melanoma overdiagnosis and compares diagnostic behaviors associated with these perceptions.

Utility of a Model for Predicting the Risk of Sentinel Lymph Node Metastasis in Patients With Cutaneous Melanoma

Michael A. Marchetti, MD; Stephen W. Dusza, DrPH, MPH; Edmund K. Bartlett, MD

Abstract Full Text

JAMA Dermatol. 2022;158(6):680-683. doi:10.1001/jamadermatol.2022.0970

This decision-analytic study examines the association of clinical benefit with use of the i31-GEP-SLNB model for sentinel lymph node biopsy selection using a 5% risk threshold.

Editor's Note
Decision Curve Analysis and the Net Benefit of Novel Tests
Adewole S. Adamson, MD, MPP; Ivo Abraham, PhD

JAMA Dermatol

Editor's Note

Decision Curve Analysis and the Net Benefit of Novel Tests

Adewole S. Adamson, MD, MPP; Ivo Abraham, PhD

Abstract Full Text

JAMA Dermatol. 2022;158(6):684. doi:10.1001/jamadermatol.2022.0976

Images in Dermatology

Yellow Urticaria

R. Matthew McLarney, MD; Warren R. Heymann, MD

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JAMA Dermatol. 2022;158(6):685. doi:10.1001/jamadermatol.2022.0597

This case report describes a man in his 70s with dark urine in the setting of increased acetaminophen use, a pruritic rash, scleral icterus, jaundice, and well-circumscribed, bright yellow papules and plaques on his lateral abdomen.

Flagellate Mushroom Dermatitis

Jade N. Young, BS; May Elgash, MD

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JAMA Dermatol. 2022;158(6):686. doi:10.1001/jamadermatol.2022.0605

This case report describes long flagellate streaks composed of red papules distributed across the trunk and extremities.

JAMA Dermatology Clinicopathological Challenge

Progressive Skin Depressions in a Child鈥檚 Neck

Jiang-Wei Cheng, MD; Zhen-Ting Lin, MD; Jiu-Hong Li, MD, PhD

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JAMA Dermatol. 2022;158(6):687-688. doi:10.1001/jamadermatol.2022.0760

A 2-year-old girl who was otherwise healthy presented with a 10-month history of asymptomatic skin depressions in her neck, nape, and submandibular regions. What is your diagnosis?

Painful Erythematous Plaques on the Trunk

Byeong Chang Ko, MD; Hai-Jin Park, MD, PhD; Mira Choi, MD, PhD

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JAMA Dermatol. 2022;158(6):689-690. doi:10.1001/jamadermatol.2022.1371

A woman in her 40s presented with painful erythematous plaques on her trunk that developed 2 months earlier and progressively spread. What is your diagnosis?

JAMA Dermatology Patient Page

Pseudofolliculitis Barbae

Tejesh S. Patel, MD; Yoseph Dalia, MD, MBA

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JAMA Dermatol. 2022;158(6):708. doi:10.1001/jamadermatol.2022.0077

This Patient Page describes the symptoms, diagnosis and testing, and treatment of pseudofolliculitis barbae.

Research Letter

Association of Body Lice Infestation With Hemoglobin Values in Hospitalized Dermatology Patients

Nora Rudd, BS; Adam Zakaria, BA; Michael A. Kohn, MD, MPP; et al.

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JAMA Dermatol. 2022;158(6):691-693. doi:10.1001/jamadermatol.2022.0818

This retrospective study examines the association of lice infestation with iron-deficiency anemia and risk factors such as homelessness and physical disability.

Evaluation of the Dermatology Physician Assistant Workforce in the US

Justin D. Arnold, MD, MMSc; Kasey Puckett, MPH; Colette Jeffery, MA; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(6):693-695. doi:10.1001/jamadermatol.2022.1026

This cross-sectional study examines the characteristics of dermatology physician assistants in the US from 2013 to 2018.

Annual Health Care Utilization and Costs for Treatment of Cutaneous and Anogenital Warts Among a Commercially Insured Population in the US, 2017-2019

Ronald Berna, BS; David J. Margolis, MD, PhD; John S. Barbieri, MD, MBA

Abstract Full Text

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JAMA Dermatol. 2022;158(6):695-697. doi:10.1001/jamadermatol.2022.0964

This cohort study evaluates annual health care utilization and costs associated with common cutaneous and anogenital wart treatments, such as cryotherapy, intralesional immunotherapy, and prescription topical treatments.

Observation

Treatment With Dupilumab for Refractory Cutaneous B-Cell Pseudolymphoma

Tejas P. Joshi, BS; Madeleine Duvic, MD; Carlos A. Torres-Cabala, MD; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(6):697-699. doi:10.1001/jamadermatol.2022.0613

This case report describes a 76-year-old man who presented with multiple nonscaly, pink, pruritic nodules, plaques, and tumors of 6 years duration on his face.