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This study compares long-term outcomes of instantaneous wave-free ratio and fractional flow reserve-based strategies to guide revascularization.

This cohort study examines changes in risk-adjusted transcatheter aortic valve replacement (TAVR) outcomes from 2019 to 2022 using data from the Society of Thoracic Surgeons (STS)/American College of Cardiology (ACC) Transcatheter Valve Therapies (TVT) Registry.

This Viewpoint describes age-specific risk thresholds for cardiovascular disease prevention therapies.

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

This systematic review and network meta-analysis investigates the optimal duration of dual antiplatelet therapy in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention with drug-eluting stents.

This prespecified secondary analysis of a randomized clinical trial evaluates clinical and hemodynamic outcomes by valve type in transcatheter aortic valve replacement among women with small aortic annuli.

This case report describes a diagnosis of ventricular septal rupture in a patient in his 70s after ST-segment elevation myocardial infarction (STEMI) due to right coronary artery occlusion.

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary prevention of sudden cardiac death, hospitalization for heart failure, and use of a pacemaker among patients with chronic Chagas cardiomyopathy.

This randomized clinical trial investigates the feasibility, safety, and efficacy of endovascular right-sided splanchnic nerve ablation for volume management in heart failure with preserved ejection fraction (HFpEF).

This study examines the projected population-level benefit of optimal guideline-directed medical therapy use globally among patients with heart failure with reduced ejection fraction.